A new study shows that some are 'immune' to CRISPR. What does it mean for biology's breakthrough editor?
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3 peer comments
Alireza Edraki
Evolutionary Biology
University of Massachusetts Medical School
My name is Ali and I study natural inhibitors of CRISPR-Cas9. Cas9 genome editing has revolutionized medicine, but we need an off-switch for it to have better control over its action. Thankfully, nature has already designed that for us. I study proteins from phages that can inhibit Cas9 and my research aims to use these proteins to turn Cas9 off in human cells whenever we desire.
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We still don't know all the consequences of gene manipulation
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